منابع مشابه
Immunosuppression and Malignancy
The increasing use over the past decade of powerful immunosuppressive drugs provides an opportunity for testing the validity of the theory that cancer results from a breakdown of the body's "immunological surveillance." This concept, first proposed by L. Thomas' and since developed by Sir Macfarlane Burnet,2 holds that such a breakdown allows the proliferation of abnormal cells, with the eventu...
متن کاملImmunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipients.
The success of renal transplantation may be counterbalanced by serious adverse medical events. The effect of immunosuppression on the incidence of de novo neoplasms among kidney recipients should be monitored continuously. Using data from the Scientific Registry of Transplant Recipients, we studied the association of induction therapy by immunosuppression with antilymphocyte antibodies, with th...
متن کاملUrinary Melatonin Levels and Skin Malignancy
Melatonin inhibits tumor genesis in a variety of in vivo and in vitro experimental models of neoplasia. In industrialized societies, light at night, by suppressing melatonin production, poses a new risk for the development of a variety of cancers such as breast cancer. This effect on skin has been previously studied only in animals and not in humans. Our goal was to examine the relationship bet...
متن کاملImmunosuppression minimization: current and future trends in transplant immunosuppression.
The past decade has witnessed unprecedented advances in renal transplantation propelled by novel and effective immunosuppression drugs. The introduction of mycophenolate mofetil (MMF), tacrolimus, cyclosporine microemulsion, sirolimus, a new generation of monoclonal antibodies (the anti–interleukin-2 receptor blockers, daclizumab and basiliximab), and the depleting polyclonal biologic Thymoglob...
متن کاملSunscreen and immunosuppression.
Recently, Walker and Young (1997) reported that ultraviolet (UV) B sunscreens offer the same UVB protection factors against inflammation and immunosuppression in the mouse . The authors studied the relationship between photoprotection of inflammation and immunosuppression with monochromatic (Phi lips TL-01 tubes, A..,. _,= 311mll) UVB radiation. T he UVB dose-response curve for murine edema was...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5834.235-c